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What is tretinoin Cream UK?
Tretinoin Cream has been the most effective molecule against acne in the last fifty years. It is known as all-trans retinoic acid (ATRA) and it belongs to the great family of retinoids. If you compare it to retinol, it is a derivative molecule of Vitamin A. However, it is a lot more powerful and it has a direct effect on the human skin cells, being one revolutionary medicine for dermatology.
First, tretinoin represents the active form of Vitamin A that means that unlike retinol, that has to be converted by the skin to retinoic acid; this is not true for tretinoin. On the contrary, tretinoin is the active substance of retinoic acid, as a result, it is the most potent and active form of Vitamin A that can act directly on skin cells and bring some beneficial effects.
Tretinoin Cream is available as a per os medication, topical cream, gel or lotion. Due to the great power, that tretinoin has and the potential side effects, it is a prescription only drug and needs special precautions before use.
Best Face Cream Products
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Active Ingredient (Generic Name): Tretinoin Indication: Acne, Pimple Manufacturer: Menarini India Pvt Ltd Packaging: 20g in Gel Strength 0.1% Delivery Time 6 To 15 days -
Active Ingredient (Generic Name): Adapalene Indication: Acne Manufacturer: Galderma India Pvt Ltd Packaging: 15 gm in 1 tube Strength 0.1% Delivery Time 6 To 15 days -
Active Ingredient (Generic Name): Azelaic Acid Indication: Acne Manufacturer: Micro Labs Limited Packaging: 15 gm in 1 tube Strength 20% Delivery Time 6 To 15 days -
ctive Ingredient (Generic Name): Betamethasone Indication: Allergy symptoms Manufacturer: GlaxoSmithKline Pharmaceuticals Ltd Packaging: 20g & 30g Tubes Strength 20g Delivery Time 6 To 15 days
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Active Ingredient (Generic Name): Tretinoin Indication: Acne, Pimple Manufacturer: Menarini India Pvt Ltd Packaging: 20g in Gel Strength 0.1% Delivery Time 6 To 15 days -
Active Ingredient (Generic Name): Adapalene Indication: Acne Manufacturer: Galderma India Pvt Ltd Packaging: 15 gm in 1 tube Strength 0.1% Delivery Time 6 To 15 days -
Active Ingredient (Generic Name): Azelaic Acid Indication: Acne Manufacturer: Micro Labs Limited Packaging: 15 gm in 1 tube Strength 20% Delivery Time 6 To 15 days -
ctive Ingredient (Generic Name): Betamethasone Indication: Allergy symptoms Manufacturer: GlaxoSmithKline Pharmaceuticals Ltd Packaging: 20g & 30g Tubes Strength 20g Delivery Time 6 To 15 days
How to Use Tretinoin Cream in Skincare Routine
One of the key factors to feel great with tretinoin cream would be to start using it gradually and apply the cream in small portions on your facial skin. That means you should slowly start to integrate tretinoin cream to your daily skincare routine so that you feel no irritation and have the best possible benefits. Here are the steps you need to take and of course, you need to always talk to your dermatologist to get the best possible advice:
- Start by using it through the night: Getting a tretinoin treatment means that you need to check your skin for irritations. Tretinoin is photosensitive and it breaks down when it comes to direct exposure of sunlight. Therefore, if you want to have an irritation-free skin you had better use it during nighttime to get the maximum of its effects without any side effect.
- Begin using tretinoin cream slowly and gradually: The lowest concentration prescribed for tretinoin cream is as low as 0.025% and you can use it not that often (better 2 or 3 times a week). Then you can gradually increase the frequency of tretinoin cream application so that you can be sure that your skin tolerates its presence.
- Make sure that you apply tretinoin cream on dry skin: The best possible practice would be to clean and pat your skin and then wait for 20 minutes before applying, so that you can be sure that the skin surface is completely dry. When you have a soggy skin, it is more possible that tretinoin passes through the pores and lead to skin irritation.
- Be aware of the quantities you use: Tretinoin cream should be used carefully and in very small portions. A pea-size portion is good for the whole facial skin area and you need to remember that using more does not accelerate its action, but it only causes more irritation and side effects.
- Apply moisturizer when you are done with tretinoin cream: Tretinoin cream can easily remove water from your skin cells so you had better apply a moisturizer to feel better.
- Always apply some sunblock cream when using tretinoin: When you use tretinoin cream, you make your skin a lot more irritable by the sunrays. You need to apply a sunblock cream with at least an SPF 30 every morning to ensure that you will have no issues with the sun when you go outdoors.

Tretinoin vs Adapalene vs Tazarotene vs Retinol
Here is a comprehensive guide of comparison between the major retinoids:
- Tretinoin vs Retinol: Retinol is an over the counter drug and it has been the very first retinoid to be available in formulations. Retinol needs to convert to retinoic acid on the skin using a two-step conversion method that severely limits its power. Today retinol is used only as an anti-aging substance as its healing power is completely limited. It has no side effects and it is quite stable and works best in people with sensitive skin that don’t care to have some mild skin irritation.
- Tretinoin vs Adapalene: Adapalene is available as a topical skin cream in most countries, with a concentration up to 0.3%. However, as the concentrations rise there is the need for a prescription. It can securely bind to several retinoic acid receptors in the skin cells and it is quite more targeted than tretinoin, making it possible to have effects that are more beneficial. It is stronger than retinol and definitely comparable to tretinoin lower doses for treating acne. Adapalene uses are for treating acne vulgaris and anti-aging or even hyperpigmentation in some patients. The drug is more photostable than tretinoin and can be with benzoyl peroxide in topical creams without any issue.
- Tretinoin vs Tazarotene: Tazarotene is a third generation retinoid drug that is prescription only in many countries. It is considered to be the most potent retinoid agent available in topical creams. Its active substance is tazarotenic acid and it can take this form within the skin cells after local application. Tazarotene can irritate the skin more than tretinoin and that is why it is prescribed in severe acne cases or for patients who have built up tolerance against tretinoin.
What is tretinoin good for?
As we mentioned above, tretinoin is a powerful medication for acne and anti-aging. It is one of the strongest retinoids available and is considered to be the gold standard for the skin care in modern medicine. So to sum up, tretinoin is the therapy of choice for acne vulgaris, it shows antiaging and photoaging effects (reducing the damage skin cells have accumulated from sun rays), it assists skin to have a clear tone improvement and brighten, and finally it regulates the pores function and prevents them from getting clogged.
What is tretinoin NOT as good for?
Even though tretinoin is the key drug for many dermatological issues, it is not good for the following cases:
- It cannot offer instant results: Patients taking tretinoin should be willing to wait and have patience to ensure they will have the cleansing results on their skin.
- Not good for sensitive skin or particular skin conditions: Tretinoin is definitely not as good as a drug for irritated skins and rosacea or eczema.
- Deep wrinkles: Tretinoin does not work well with deep wrinkles and may not show the same antiaging effect.
Does tretinoin thin the skin or thicken it?
There is a great misconception that tretinoin thins the skin and it should not be used by people who already have a thin skin layer. However, the reality is that tretinoin does not thin the skin, but on the contrary it thickens it especially in the lower layers. To be more precise tretinoin can thin the outer layer of the dermis and thicken the epidermis to ensure that new skin cells will easily appear and create a stunning skin view after applying it for a certain amount of time.
Where can I buy tretinoin Cream UK?
There are many places besides your local pharmacy store that you can get tretinoin Cream UK. For instance, you can buy tretinoin online at the most reputable sites like https://tretinoincream.uk, which will never ask for a prescription and will be happy to ship you tretinoin in topical cream to deal with any skin needs you may have.
Remember that when you are taking tretinoin it’s always better to seek advice from your dermatologist and make sure that you are taking it in the right form and concentration that could maximize the benefits for your skin, while the same time minimize the side effects of this drug.
I’ve recently been prescribed tretinoin. What important information should I be aware of?
If you have recently started, taking tretinoin here is the important information you should always be aware of:
- Expect some minor side effects during the initial adjustment period. Eight to ten weeks is the bare minimum for acne, while six to twelve months is the adjustment period for antiaging use.
- Make sure you know and understand the best application practices for tretinoin. You need to use it during the night, apply it on dry skin and always use the least possible portion. In addition, you need to avoid sensitive areas around the eyes, nose, and mouth to ensure there is no irritation there.
- Always apply sun protection when going out. Tretinoin will make your skin red so you better be prepared with a good sunblock when you face the sun.
- Do not use other exfoliating products when you take tretinoin.
- Avoid taking tretinoin when you are pregnant or breastfeeding.
General routine tips
Here are some general routine tips for tretinoin that anyone should be aware of:
- Expect the results to come in a few weeks.
- Do not overdo it with the quantities you use.
- Apply tretinoin at night for better results and fewer side effects.
- Never apply tretinoin on moisture skin as it can enter your pores easily.
- Avoid any other active substance for your skin.
- Hydrate your skin when you are done with tretinoin therapy.
If you follow all these tips, you will take the most benefits out of your tretinoin treatment.